Contributed by: Dennis Fortier, President, Medical Care Corporation
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A new study suggests that Memantine, a drug currently approved for treatment of the late stages of Alzheimer's disease, might also be effective in early stages.
In animal based experiments, rats were taught to find their way through a water maze and then given agents to induce brain inflammation. Consistent with theories suggesting that inflammation impairs cognitive function, the rats essentially "forgot" how to navigate the maze. However, once given Memantine, the rats' performance normalized and they were once again able to complete the maze.
Obviously, this is early-stage work but the hypothesis has theoretical validity and the earliest empirical data are encouraging.
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