Showing posts with label Physcial Exercise. Show all posts
Showing posts with label Physcial Exercise. Show all posts

6 Ways to Prevent Memory Loss

Contributed by: Dennis Fortier, President, Medical Care Corporation
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This summary, published online today at Fox News, cites evidence supporting 6 lifestyle choices you can make to reduce the likelihood of cognitive decline.

Of course, there are no guarantees and bad genes combined with age can overwhelm even the best life-style.  Nonetheless, it is worthwhile to know the steps that might help, and to pursue as many of them as possible.

I suggest you click through and read the short story, but here is the list:
  1. Stay Physically Active
  2. Eat Fruits and Veggies
  3. Reduce Risk Factors for Heart Disease
  4. Embrace Cultural Activities
  5. Care for Your Teeth
  6. Challenge your Intellect
Remember, there is no certain method to eliminate all risk of cognitive decline, but doing what you can to stack the odds in your own favor seems like an attractive course of action.

Recent Press on Preventing Alzheimer's



 Contributed by: Dennis Fortier, President, Medical Care Corporation



There is no hope? 

Eating well, staying fit, and using your brain have no effect on your risk for Alzheimer's?  Many headlines have implied this dire message over the past 24 hours.

The source of these headlines is an article published in the Archives of Neurology, online edition.  The article reviewed the evidence that actively managing modifiable factors could reduce the risk of AD, and concluded that only a low level of evidence suggests a relationship between the risks and the disease.

Let's be sure not to misunderstand this.

What is a "Low Level" of Evidence?
The authors classified the level of evidence for each risk factor in accordance with accepted scientific standards.  These standards allow for three levels of evidence: low, medium, and high. 

Importantly, a "low" level of evidence means that real research, conducted with sound methods, that was published in peer-reviewed medical journals, showed an association between the risk factor being studied and the incidence of AD.  Perhaps the association was not overly strong, perhaps the sample size was small, perhaps similar studies have not been completed to verify the result, but even a "low" level of evidence is a pretty good start in finding a meaningful association.

The panel authoring this paper, on behalf of the National Institutes of Health, found a low level of evidence that diabetes, high cholesterol, and tobacco use all confer a higher risk of Alzheimer's disease.  Sure we want more evidence and a higher level of confidence, but all work so far suggests that these are real risks that need to be managed.

The panel also found a low level of evidence that a Mediterranean diet, folic acid intake, light alcohol consumption, cognitive activity, and physical activity all reduced risks of Alzheimer's.  That's more good news.

This review constitutes unbiased, expert confirmation that many modifiable risk factors should in fact be managed to reduce the risk of AD.  The evidence is not as strong as we would all like, but it has reached a minimum threshold of scientific scrutiny to establish a likely association.

The problem here is the massive and consistent misinterpretation of these findings by the press.  In every day jargon, a "low level of evidence" is a negative testimonial as to the likelihood of an association.  But in the scientific world, where facts are closely scrutinized before they qualify as "evidence", a low level of evidence connotes a pretty good start toward proving a point.  It is a shame that this is not understood by the major media outlets and is not more clearly represented in their publications.

6 Ways to Keep Your Brain Healthy

Contributed by: Dennis Fortier, President, Medical Care Corporation
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There is some great advice in the Huffington Post regarding 6 well-validated approaches to maintaining a healthy brain.  Each of these has been covered to some extent in past posts here, but this is a nice presentation of the evidence in one article.

While I would recommend that you click through and read the full article, the 6 tips are listed here as an overview:
  1. Manage chronic conditions under your control
  2. Incorporate Mediterranian diet
  3. Stay physically active
  4. Avoid Tobacco Smoke
  5. Stay intellectually and socially active
  6. Watch for signs of Depression
Each of these is well within your control and proven to reduce your risks for cognitive decline.

Physical Exercise Boosts Brain Health

Contributed by: Dennis Fortier, President, Medical Care Corporation
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We have discussed similar evidence in many earlier posts, but when new studies garner lots of press, we like to weigh in and share our perspective.  Especially on research that suggests new insights into how and why physical exercise benefits the brain.

In a new study published in the Proceedings of the National Academy of Sciences, walking was once again shown to improve brain health, this time as demonstrated by hippocampul volume.  The hippocampus is a small region in the brain where short-term memory is processed.  It is known to shrink as we age and it's relative size has been shown to correlate with memory capacity.

In this study, 120 sedentary adults between the ages of 55 and 80 were divided into two groups.  One group began a regimen of regular walking while the other began a regimen of stretching and toning. After one year, the group that walked showed an average increase in hippocampul volume of about 2% whereas the other group, who did not participate in aerobic exercise, showed an average decrease in hippocampul volume of about 1.5%.

What is most notable in this study is that the walking regimen was fairly minimal.  The expansion of the hippocampus and a measured improvement in spatial memory were obtained by walking for just 40 minutes per day, three days per week.

Given the potential benefits for such a minimal effort, it seems like we should all consider embracing the habit of a short, regular walk.

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5 Brain Healthy Resolutions for 2011


Contributed by: Dennis Fortier, President, Medical Care Corporation
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It is that season when it is enjoyable, and in some ways instructive, to pause and reflect on the passing of another year. It is also an excellent time for setting priorities and establishing habits that we will be happy to reflect upon twelve months from now. With that in mind, this article suggests 5 simple practices with clear “brain health” benefits that you may wish to consider as you embark on a fresh new year.

To be sure, there are higher ideals than those I have listed here, toward which we could all strive. However, my intention is to provide readers with some ideas that are relatively easy to pursue but can still yield important benefits; the goal is to offer maximal return for minimal effort and sacrifice.

With that said, here are five considerations for starting fresh in 2011:

1. Improve Cardio-Vascular Health

This suggestion is not new but deserves repeating because it has been proven beyond a doubt that good cardio-vascular health leads to better over all health and lower risks for heart disease, diabetes, and Alzheimer’s disease. What is new is certain evidence about how easy it may be to start moving the needle in the right direction.

Improving cardio fitness need not involve strenuous exercise and really doesn’t even require that you sweat. Walking is one of the overall best and most underrated forms of exercise and can often be incorporated into daily errands. Also, don’t think that because walking is easier than running or swimming that you must do it longer to gain a benefit; a daily 30-minute walk is immensely beneficial to a person with no current routine of physical exercise. Especially if the walk can be augmented with a few trips up and down the stairs in lieu of the usual elevator ride.

In terms of staying motivated to maintain a routine of physical exercise, try to find a quantitative measure that will reveal your progress and keep you looking for more gains. In the past, much emphasis has been placed on body weight, a measure that is easy to obtain but can be difficult to improve. As an alternative, check your pulse rate at the end of your work out and track it for one month of daily walks; you might be surprised to see it fall. When you consider how many beats of your heart you can save over the course of a year by keeping your heart rate low, it can be very motivating.

Also, whether or not you suffer from high blood pressure or high cholesterol, be sure to get these measures from your physician during your next check-up and keep track of them as you exercise. Even something as simple as a daily walk is good for your brain and can produce meaningful improvements in both of these bio-markers as you gain better fitness.

2. Reduce Stress

This suggestion might top the all time list of things that are easy to suggest but difficult to achieve. However, it turns out that for many of us, a high percentage of the daily stresses we encounter are self-inflicted. That’s right; choices we make and attitudes we willingly assume end up creating stress that we could otherwise avoid.

Reducing stress is important because we know how detrimental stress can be to our health. Real physical processes are triggered by emotional reactions to stress and, as far as our science can tell, none of those processes are beneficial while all have harmful side effects.

Here is a simple suggestion for reducing stress that, although it won’t work for all of you, must be tried by the rest of you before you can fully believe its effects. Put simply, you should make a conscious decision to drive with patience and courtesy. Look for other drivers trying to cut traffic and motion them in. Don’t speed up to close the gap when another car wishes to enter your lane; slow down and allow them in. Embrace yellow lights for the opportunity they foretell to pause for a moment – this is certainly less stressful than treating them as a threat to your rapid progress. Don’t tailgate or change lanes incessantly seeking opportunities to move one car length closer to the front of the crawling traffic; it is just not worth it. Instead, accept the pace, listen to some music, and keep an eye out for other drivers who might benefit from your courteous cooperation.

If you are not aggressive driver and cannot benefit from that tip, perhaps you can benefit from becoming a less aggressive “parker”. When visiting an establishment with a large parking lot, rather than seeking the spot nearest to the entrance, subjecting yourself to the anxiety of passing up a mediocre spot for the possibility of finding a better one, all the while monitoring the flow of motorists who might be competing for the best spot, try driving to the far end of the lot and parking in the open expanse of remote spots. It is a stress-free approach with the added benefit of a short cardio workout as you walk to your final destination.

While this might seem silly, it’s a step toward avoiding self-inflicted stress that just might carry over into other realms of your life as well. Get the right attitude, reduce your stress, and enjoy a healthier brain and body.

3. Stay Socially Active

While most of us are not in danger of becoming accidental hermits, making new friends and interacting socially are activities that have been documented to decline as we age. We are most prolifically social as young students, followed by fairly intense socialization in adulthood when our children are students, and we tend to be least active when we are older and our children have grown and moved on.

Much research on the benefits of intellectual stimulation, the act of using our brains in challenging ways, has shown a positive correlation with maintained cognitive health. I will write more on that below but will make a separate point here. Meeting people, learning about them, interacting and cooperating with groups, and cultivating relationships are all activities that require deep and comprehensive cognitive activity. In socializing, especially with persons we are still getting to know, we use memory, verbal skills, and judgment along with a poorly understood melding of emotions and executive function. In the opinion of many scientists, socializing may be the best mental activity we have.

Two great ideas for remaining socially active are club membership and volunteering. While you may or may not have interests that lend themselves easily to club membership, a regular card game or social activity with a committed group brings the same benefits. As for volunteering, hospitals, churches, and many non-profit organizations are begging for help in nearly every community. Incidentally, one of the most meaningful gifts you can offer through volunteering is friendship and interaction with a lonely, usually elder, person. Doing so will yield a double benefit because every interaction will be a work-out for both of your brains, not to mention the good it will do for your hearts.

4. Eat Well

You had to know this one was coming. As I did with the section on cardio-vascular fitness, I will try to present this in a new perspective that might be easier to embrace than those perspectives you have heard in the past.

Here is my fresh take on eating well. You needn’t necessarily deny yourself the junk food you’ve grown to love nor worry too much about your daily intake of calories. You do need, however, to worry about getting proper nutrition first. While consuming empty calories is harmful because it leads to weight gain and poor vascular health, the more damaging impact is that it strips away your appetite and prevents consumption of necessary vitamins and nutrients. A fresh approach to diet in the new year might be to focus first on what you should eat and set, as a second goal, the elimination of foods that you should not.

The good news is that the diet shown to produce the best vascular health was also shown this year to also promote the best cognitive health. One should be sure to consume a diet rich in cruciferous and green leafy vegetables, nuts, fish, and tomatoes and low in red meat and high-fat dairy products. Ideally, you will eventually adopt a diet whereby you take in what you need and avoid what you do not, but an easy place to start is to ensure that you get enough fruits and vegetables prior to filling up on junk; this will offer the best opportunity to keep your brain functioning at a high level in the new year.

5. Seek Intellectual Stimulation

If you have pondered the health of your brain at all, you have likely read or heard about the importance of ongoing intellectual stimulation. While it is not yet completely understood, it does appear that active brains decline more slowly with age than those that are relatively unchallenged.

A potential red herring in the discussion is the value of crossword puzzles, sudoku, and the like. Yes, they are mentally challenging activities but they may not produce the rich neural rewards that other activities, such as socializing, might yield. The key seems to be related to the concept of “learning”. If you don’t know the rules of crossword or sudoku then these may be great activities for your brain. However, if you know how the games are played, then merely working through new forms of each puzzle requires no new learning and may offer few benefits to brain health.

Among the most challenging yet rewarding intellectual activities that you pursue are learning to play a musical instrument and learning to speak a foreign language. Both of these have become much easier in the digital age with the advent of tools and software to aid in the learning process. While this might seem counter-intuitive it is actually quite well-grounded. With better tools, the learning becomes easier so the process yields faster proficiency and remains interesting through time. Despite the ease, the learning is real and the brain builds new circuits in accordance with the new learning. The whole process can be great fun, deeply rewarding, and very good for your brain.

So there you have 5 good suggestions to start fresh in the new year and keep your brain healthy in the process. Work on that cardio-vascular fitness, reduce your stress, stay socially active, eat well, and challenge your brain with new learning. If you do so, you can expect that twelve months from now you can look back with clarity and reflect on a year when you made a worthy commitment to the health of your brain.

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More Evidence that Walking is Good for the Brain

Contributed by: Dennis Fortier, President, Medical Care Corporation
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For the second time in as many months, a major study has shown that a regular walk leads to better brain health.

We recently posted this analysis of data from the Cardiovascular Health Study - Cognition Study showing that regular walking over a period of years preserved brain volume. Now, further analysis of the same data set was presented at the Radiological Society of North America showing that cognition was preserved among walkers at a significantly better level than among a sedentary group.

The data are compelling; a regular daily walk is good for you.
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A better understanding and more awareness of Alzheimer's related issues can impact personal health decisions and generate significant impact across a population of aging individuals. Please use the share buttons below to spread this educational message as widely as possible.

A Daily Walk is Surprisingly Good for Your Brain

Contributed by: Dennis Fortier, President, Medical Care Corporation
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We often cite research that correlates physical fitness with brain health. Surveys have shown, however, that many read the phrase "physical fitness" and conjure images of gym memberships and grueling workouts. Such a perspective may be a deterrent for those who assume that minimally intense workouts yield no benefits.

This post aims to dispel the notion that only an intense physical exercise is helpful.

Research published online yesterday in Neurology shows that a brief regular walk may meaningfully reduce the likelihood Alzheimer's disease. Specifically, the research showed a significant correlation between walking regularly and maintaining the volume of gray matter in the brain throughout later adulthood. More importntnly, walking regularly was negatively correlated with incidence of cognitive impairment.

This evidence is very consistent with other studies that have shown a daily walk of a mile or so can be part of a fantastic regimen for long-term health. In this regard, the Alzheimer's Association's tradition of holding "memory walks" to raise awareness about the disease is especially apropos.

Walk forth and be well.
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A better understanding and more awareness of Alzheimer's related issues can impact personal health decisions and generate significant impact across a population of aging individuals. Please use the share buttons below to spread this educational message as widely as possible.

Are Alzheimer's Drugs Better than Previously Thought?

Contributed by: Dennis Fortier, President, Medical Care Corporation
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A very big story about Alzheimer's treatment is unfolding in Europe. This story is big from a news coverage point of view and also from the perspective of real world impact. I am referring to the story about the National Institute for Health and Clinical Excellence (NICE) in the U.K. that has reviewed ongoing science and reversed their earlier stance on Alzheimer's drug efficacy.

Background
In 2006 and 2007, NICE recommended against National Health Services paying for cholinesterase inhibitors (the primary class of Alzheimer's drugs) for patients with mild to moderate Alzheimer's disease. They based this recommendation on a financial analysis suggesting that the economic benefits of treating AD with those drugs (Aricept, Exelon, and Razadyne) in its mild and moderate stages did not outweigh the costs of the treatment.

Naturally, that recommendation sparked lots of debate, including an argument that most experts considered very legitimate. The argument was that "average treatment effect" is merely a composite derived from some patients who responded well to treatment and others who did not. Since it was clear that treatment has meaningful benefits for some patients, and no one can predict which patients will respond, then everyone deserves the chance to find out.

New Position
Now, based on an ongoing review of emerging data from new studies, NICE is planning to revise that recommendation. This is great news for the patients afflicted with AD who have not yet progressed to the severe dementia stage. It is also important for the effect this move will have on the global conversation and the public perception of treatment efficacy.

Optimal Treatment
The one point I think needs to be added to this story is that, the drug class in question is only one part of the robust treatment approach we know to be most effective in delaying the progression of Alzheimer's disease. Optimal treatment includes poly-therapy (cholinesterase inhibitor plus Namenda), a balanced diet, physical exercise, and tight control of other conditions such as diabetes and hypertension.
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A better understanding and more awareness of Alzheimer's related issues can impact personal health decisions and generate significant impact across a population of aging individuals. Please use the share buttons below to spread this educational message as widely as possible.

The Global Cost of Dementia


Contributed by: Dennis Fortier, President, Medical Care Corporation
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With each new study, the numbers get bigger and scarier. The latest report, The Global Economic Impact of Dementia, released by the non-profit group Alzheimer's Disease International, is no exception. The full report can be downloaded here.

At a top line level, the report estimated the annual cost of care for demented patients at over $600B or about 1% of the world's gross domestic product. Astoundingly, that figure is dwarfed by the projected rise in costs over the next decades. In fact, the report estimates that costs could reach nearly $2 trillion by the year 2050. A good summary of these findings are published online by Time.

While a cure is the goal that everyone seeks, a cold economic look at the disease makes it clear that the crippling expense of care comes primarily from patients in the moderate to severely demented stages of illness, when they cannot administer their own lives. While delaying progression to those stages might seem to be an uninspiring health care goal, it is a very attractive economic goal.

To that end, earlier intervention and robust treatment, including a balanced diet, physical exercise, pharmaceutical therapy, and tight control of diabetes and any present cardiovascular risks, should be a high priority in the primary care setting.

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A better understanding and more awareness of Alzheimer's related issues can impact personal health decisions and generate significant impact across a population of aging individuals. Please use the share button below to spread this educational message as widely as possible.

Alzheimer's Treatment: Combo-Therapy is Best


Contributed by: Dennis Fortier, President, Medical Care Corporation
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A new study presented at the 14th Congress of the European Federation of Neurological Societies (EFNS) strongly supports earlier findings about treatment efficacy of combination therapy. The research showed that, when treating Alzheimer's disease, a combination of a cholinesterase inhibitor like Aricept plus Namenda is significantly better than mono-therapy with a cholinesterase inhibitor only.

In this study of more than 400 patients with moderate to severe Alzheimer's disease, significant improvements in patients receiving combined therapy were noted in cognition, function, behavior, global outcome, and care dependency. These are robust findings that might begin to change nihilistic attitudes toward Alzheimer's treatment.

The most optimistic view of treatment efficacy comes not only from studies like this, showing the benefits of combo-therapy, but from a more robust approach. To maximize treatment effect, we need to intervene earlier in the disease process so that patients can start therapy before massive neuron death and synapse loss occurs. Additionally, we need to augment the benefits of drug treatment with a balanced diet, physical activity, and proper control of other co-morbid conditions such as diabetes ad hypertension. Most probably, staying intellectually active and socially engaged is also beneficial.

Given the generally defeatist tone of most press about Alzheimer's treatment, I am happy to see the occasional positive press about our ability to combat this disease. We have a long way to go but the facts are more comforting than most headlines suggest.

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A better understanding and more awareness of Alzheimer's related issues can impact personal health decisions and generate significant impact across a population of aging individuals. Please use the share buttons below to spread this educational message as widely as possible.

Working Out for a Healthy Brain

Contributed by: Dennis Fortier, President, Medical Care Corporation
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The LA Times published a nice article today summarizing what we know about mental and physical exercise with regards to the benefits that accrue to cognitive health.

Articles of this nature are commonly written with a commercial agenda, touting exaggerated claims that have not been adequately validated through scientific study. I have chosen to highlight this article because it was well written and objective in its presentation. I think it does a good job in separating unproven claims from those with varying degrees of scientific evidence.

We know that physical exercise is generally beneficial to overall health, including cognitive health. We also know that exercising your brain, through challenging new learning, is surely not bad and most probably beneficial. But be aware, many vendors of computerized workouts claim benefits that are yet unproven. Others are accumulating scientific evidence suggesting that their products may improve mental sharpness. It certainly stands to reason that forcing your brain to learn and to establish new synaptic circuitry is probably somehow helpful. You should simply be aware that not every claim you find online is well backed with evidence.

The bottom line: staying active (both mentally and physically), is a good bet in maintaining a high level of health and a good quality of life.
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A better understanding and more awareness of Alzheimer's related issues can impact personal health decisions and generate significant impact across a population of aging individuals. Please use the share buttons below to spread this educational message as widely as possible.

How a Short Walk Helps Your Brain

Contributed by: Dennis Fortier, President, Medical Care Corporation

Regular readers of this blog have undoubtedly seen the evidence that physical exercise is good for the brain. Most of the research in this area is based on benefits associated with improved cardio-vascular health and a more consistent, oxygen-rich supply of blood to the brain.

Now, according to research from the Beckman Institute at the University of Illinois, published online in Frontiers in Aging Neuroscience, it appears that certain neurological mechanisms also play a role in translating physical exercise into better brain health.

This research recruited a group of sedentary adults aged 59 to 80 and assigned them to one of two groups. Members of the first group walked for 40 minutes at their own pace, three times per week, for one year. Members of the other group did stretching and toning exercises with similar frequency and intensity during the same period. Cognition was measured in each of the two groups at the start, mid-point, and conclusion of the study.

As expected, the walking group demonstrated significant improvements from their baseline scores. They also showed much greater improvement than those in the stretching and toning group.

The researchers were also seeking to demonstrate any neurological benefits, in addition to the expected vascular benefits provided by the exercise. To accomplish this, they used MRI to measure activity across circuits in the subject's brains. They noted an interesting finding with regard to the default mode network (DMN) which is the circuit in the brain that is most active when the brain is at rest and relatively unengaged in other activities.

In healthy brains, the DMN quickly deactivates when the person engages in a task that requires their concentration. However, in older and/or sicker brains, the DMN tends to stay active and interferes with one's attempt to focus on a more challenging task. In this study, the subjects who walked for a year showed a significantly better ability to deactivate the DMN and focus on other tasks. This was true compared to the stretching and toning group but also true compared to their own performances at the start of the study.

This is great news on two levels. We already knew that physical exercise was beneficial to both our physical and mental health. Now it seems that a light work-out, as simple as walking at one's own pace for 40 minutes per walk, three times per week, is adequate to produce a meaningful benefit. Furthermore, the benefit is derived from two distinct mechanisms, one physical and the other neurological.
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A better understanding and more awareness of Alzheimer's related issues can impact personal health decisions and generate significant impact across a population of aging individuals. Please use the share buttons below to spread this educational message as widely as possible.

Managing Risks for Dementia


Contributed by: Dennis Fortier, President, Medical Care Corporation
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One of my favorite types of scientific research is the "review paper" when authors collect and review the literature in a certain field and report on the depth and breadth of findings in the targeted area of study. As such, I was happy to see a recent report by the BBC that the Alzheimer's Society had chaired a panel of experts and reviewed more than 70 research papers on reducing the risk of dementia.

The report contained some elements that may be as surprising as they are important. Notably, they suggested that age 35 is probably the right time to start managing known risks in an effort to ward off dementia later in life.

I strongly suggest you click to read the BBC's synopsis of the report but the highlights are noted here:

Strong Evidence in support of:
- Get Physical Exercise
- Don't Be Obese
- Bring Down High Blood Pressure
- Reduce High Cholesterol
- Don't Smoke

Some Evidence in support of:
- Drink Modest Amounts of Alcohol
- Eat a Mediterranean Diet
- Remain or Become Socially Active

The Jury is out on:
- Brain Training
- Vitamin Supplements

The importance of this review, and other similarly scientific reviews, can not be overstated in this era of aggressive commercialization of unregulated health care solutions. There is a lot of hype in the press that has not yet been scientifically validated. Some of it might ultimately prove to be worthwhile but this review let's you know the current state of the science.

How to Read the News: Part 5 of 5


Contributed by: Dennis Fortier, President, Medical Care Corporation
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The purpose of the Brain Today blog is to distill the daily news about brain health and help the public understand the essential meaning of each article. Through time however, I have found myself clarifying the same themes over and over again. Five of these themes are explored in this five-part series “How to Read the News About Alzheimer’s and Dementia”.

How to Read the News About Alzheimer’s and Dementia - Part 5 “No Cure” is not Nearly as Bad as it Sounds

For some reason, journalists feel compelled to point out the fact that Alzheimer’s has no cure. The mere mention of this basic truth tends to cast a pall over the topic and suggests a direness that is not necessary. Diabetes has no cure; hypertension has no cure; multiple sclerosis has no cure; yet all of those diseases are reported in the press with optimism about treatment that never seems to follow Alzheimer’s disease.

I concede that available treatment for Alzheimer’s disease generally yields only modest effects and sometimes none at all. However, some patients respond quite well to treatment and physicians have no way of distinguishing responders from non-responders ahead of time. For this reason, it makes sense to get all AD patients on treatment as early as possible to optimize treatment efficacy for all.

Also, the realm of treatment goes beyond the pharmaceutical arena. Solid research shows that physical activity, a good diet, social engagement, an educated caregiver, intellectual stimulation, and perhaps certain supplements are components of a robust treatment plan that can slow progression of symptoms in many patients. Reading that a single component of treatment, say a certain drug, has an unimpressive impact on disease progression is not enough to conclude that treatment is worthless.

Finally, a major barrier to effective treatment is that we generally fail to diagnose AD in a timely manner. Most patients are diagnosed after several years of symptoms when significant brain damage has already occurred and treatment is unlikely to help. Certainly we cannot cure the disease at that late stage but an earlier intervention might delay it long enough to prevent the patient from becoming demented. New drugs in the FDA approval pipeline might halt it all together.

The bottom line is that stating, “AD has no cure”, obscures the fact that it can be treated with some degree of success, for many people, especially when diagnosed in an early stage. Many diseases have no known cure but we manage them in the medical system with a sense of purpose and optimism. We need to approach AD in a similar manner.

Here are the links to each other part of this series:
Part 1 of 5: Be Aware of the Author's Definition of AD
Part 2 of 5: Don't be Mislead by Data on Treatment Efficacy
Part 3 of 5: Common Assertions about Diagnostic Accuracy Hide Truth
Part 4 of 5: The Term "Dementia" Cannot be Interpreted Loosely